The People of Tulane Cancer Center Research

Janarthanan JayawickramarajahJanarthanan Jayawickramarajah, PhD
Assistant Professor of Chemistry
Tulane Cancer Center Contributing Member

Contact Information
Phone: 504-862-3580
Address: 2015 Percival Stern Hall, 6400 Freret St., New Orleans, LA 70118

Biographical Narrative

Janarthanan Jayawickramarajah received his B.S. degree (with honors) in chemistry and a minor in anthropology from the University of North Carolina at Chapel Hill in 2000. He obtained a Ph.D. in organic chemistry from the University of Texas at Austin in 2005. For his graduate work on molecular recognition and self-assembly of synthetic nucleic acid bases, he has received the Dorothy Banks Research Fellowship and The College of Natural Sciences Dean's Excellence Award. After completion of a postdoctoral stint at Yale University focusing on protein recognition and DNA self-assembly, he joined the faculty at Tulane (August 2007). Currently, his research focuses on the development of designer molecules that have the unique ability to undergo specific molecular recognition events in a stimulus responsive manner.

Selected Publications
Harris DC, Chu X, Jayawickramarajah J. DNA-small molecule chimera with responsive protein-binding ability. Journal of the American Chemical Society, 2008 Oct 15 (epub ahead of print).

Pierce SE, Sherman CL, Jayawickramarajah J, Lawrence CM, Sessler JL, Brodbelt JS. ESI-MS characterization of a novel pyrrole-inosine nucleoside that interacts with guanine bases. Anal Chem Acta. 2008 Oct 3;627(1):129-35. Epub 2008 Apr 15.

Jayawickramarajah J, Tagore DM, Tsou K, Hamilton AD. Allosteric control of self-assembly: modulating the formation of guanine quadruplexes through orthogonal aromatic interactions. Angew Chem Int Ed Engl. 2007;46(40):7583-6.

Tagore DM, Sprinz KI, Fletcher S, Jayawickramarajah J, Hamilton AD. Protein recognition and denaturation by self-assembling fragments on a quadruplex scaffold. Angew Chem Int Ed Engl. 2007;46(1-2):223-5.

Sessler JL, Lawrence C, Jayawickramarajah J. Molecular recognition via base-pairing. Chem Soc Rev, 36:314-325, 2007.


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