The People of Tulane Cancer Center Research
Yan Dong, Ph.D.
B Cao, X Liu, J Li, S Liu, Y Qi, Z Xiong, A Zhang, T Wiese, X Fu, J Gu, PS Rennie, O Sartor, BR Lee, C Ip, L Zhao, H Zhang, and Y Dong. (2013) 20(S)-Protopanaxadiol-aglycone Downregulation of the Full-length and Splice Variants of Androgen Receptor. International Journal of Cancer, 132, 1277–1287. PMID: 22907191
Y Zhan, B Cao, Y Qi, S Liu, Q Zhang, W Zhou, D Xu, H Lu, O Sartor, W Kong, H Zhang, and Y Dong. (2013) Methylselenol Prodrug Enhances MDV3100 Efficacy for Treatment of Castration-Resistant Prostate Cancer. International Journal of Cancer, 2013 Apr 11. doi: 10.1002/ijc.28202. [Epub ahead of print]. PMID: 23575870. Featured in “MDLinx”.
Alison Egan, Yan Dong, Haitao Zhang, Yanfeng Qi, Steven P Balk, Oliver Sartor. (2013) Castration-Resistant Prostate Cancer: Adaptive Responses in the Androgen Axis. Cancer Treatment Reviews, 2013 Sep 14. [Epub ahead of print]. PMID:24139549
Y Qi, X Fu, Z Xiong, H Zhang, SM Hill, BG Rowan, and Y Dong. (2012) Methylseleninic Acid Enhances Paclitaxel Efficacy for the Treatment of Triple-Negative Breast Cancer. Plos One, 7, e31539.
R Gao, L Zhao, X Liu, BG Rowan, M Wabitsch, DP Edwards, Y Nishi, T Yanase, Q Yu, Y Dong. (2012) Methylseleninic Acid is a Novel Suppressor of Aromatase Expression. Journal of Endocrinology, 212, 199–205. PMID: 22128327. - one of the top downloaded research articles from the journal website.
H Zhang, J Fang, D Yao, Y Wu, C Ip, and Y Dong. (2010) Activation of FOXO1 Is Critical for the Anticancer Effect of Selenium in Prostate Cancer Cells. Prostate, 70, 1265-1273. PMID: 20623629
S Liu, Y Qi, Y Ge, T Duplessis, BG Rowan, C Ip, H Cheng, PS Rennie, I Horikawa, AJ Lustig, Q Yu, H Zhang, and Y Dong. (2010) Telomerase as an important target of androgen-signaling blockade for prostate cancer treatment. Molecular Cancer Therapeutics, 9, 2016-2025. PMID: 20571066. Featured in the "MOLECULAR CANCER THERAPEUTICS Highlights: Selected Articles from This Issue."
Liu S, Zhang H, Zhu L, Zhao L, Dong Y. KLF4 is a novel mediator of selenium in growth inhibition. Molecular Cancer Research, 6:1, 2008.
Li S, Zhou Y, Wang R, Zhang H, Dong Y, Ip C. Selenium sensitizes MCF-7 breast cancer cells to doxorubicin-induced apoptosis through modulation of phospho-akt and its downstream substrates. Molecular Cancer Therapeutics, 6:1031, 2007.
Zhang H, Wu Y, Malewicz B, Lu J, Li S, Marshall JR, Ip C, Dong Y. Augmented suppression of androgen receptor signaling by a combination of alpha-tocopheryl succinate and methylseleninic acid. Cancer, 107:2942, 2006.
Dong Y, Zhang H, Gao AC, Marshall JR, Ip C. Androgen receptor signaling intensity is a key factor in determining the sensitivity of prostate cancer cells to selenium inhibition of growth and cancer-specific biomarkers. Molecular Cancer Therapeutics, 4:1047, 2005.
Dong Y, Lee S, Zhang H, Marshall JR, Gao AC, Ip C. Prostate specific antigen (PSA) expression is down-regulated by selenium through disruption of androgen receptor signaling. Cancer Res, 64:19, 2004.
Dong Y, Zhang H, Hawthorn L, Ganther HE, Ip C. Delineation of the molecular basis for selenium-induced growth arrest in human prostate cancer cells by oligonucleotide array. Cancer Research, 52:708, 2003.
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