Mishra, Anil, PhD

Anil Mishra, PhD

Dr. Anil Mishra, PhD., is Professor of Medicine and Endowed Chair, Edward G. Schlieder Educational Foundation and the Director of Tulane Eosinophilic Disorder Center at the Section of Pulmonary Diseases, Tulane School of Medicine, New Orleans, LA. Earlier, Dr. Mishra served as a faculty member at Allergy and Immunology Division, Cincinnati Children's Hospital Medical Center, Cincinnati, OH and Professor Medicine, Case Western Reserve University Medical College, Cleveland, OH before joining the Tulane University School of Medicine, New Orleans, LA.

Dr. Mishra's most important contribution was to establish that eosinophils are the resident cell that home prenatally in the gastrointestinal tract (Mishra et al. J. Clin. Invest. 1999, 103, 1719-27) and the gastrointestinal tract (esophagus to colon) constitutively expresses eotaxin-1(an eosinophil selective chemoattractant). Dr. Mishra developed a first murine model of asthma associated eosinophilic esophagitis (Mishra et al. J. Clin. Invest. 2001, 107, 83-90). His findings implicated aeroallergen in the etiology of EoE and suggested that esophageal eosinophilic inflammation is mechanistically associated with pulmonary inflammation (Mishra et al. J. Immunology 2002, 168, 2464-69 and Gastroenterology, 2003, 125. 1419-27). Most recently Dr. Mishra's laboratory showed the significance of IL-15 in recovering allergen-induced airway obstruction (J. Allergy Clin Immunology 2017) and CD274 expressed eosinophils as an possible non invasive biomarkers of EoE( Case Report in Gastroenterology, 2017).

Dr. Mishra is an elected fellow of the American Academy of Allergy Asthma Immunology (FAAAAI), and American Gastrointestinal Association (FAGA). He has over 83 articles, book chapters and reviews on molecular mechanisms of the pulmonary and gastrointestinal toxicity and allergic responses in high impact factor journals. Some of his publications are cited more than 300 to 450 till 2017. Dr. Mishra's research has been supported by the 2-different institutes (NIDDK and NIAID) of National Institutes of Health to understand the initiation and progression of EoE pathogenesis. He is serving in a number of study sections as member in NIH. More recently, his research implicated iNKT cells to the food and indoor insect allergens induce EoE and iNKT cell neutralization as a possible future therapy of EoE (Clinical and Translational Immunology, 2013). He patents IL-15 responsive T cell associated molecules as a non-invasive biographers for EoE that differentiate EoE from GERD. Current interest is on the role of IL-15 and IL-18 in pulmonary and gastrointestinal eosinophilic inflammation and rIL-15 treatment strategy for airway hyperactivity and lung or other tissue fibrosis.

If interested in his research publications, grants, awards and honors go to his Publication list and visit the website of Dr. Mishra's Research Laboratory and Tulane Eosinophilic Disorder Center.

1430 Tulane Ave, New Orleans, LA 70112 504-988-2250