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Publications

 

July 2015 - June 2016

Faculty Publications

Therapeutic Role of Interleukin 22 in Experimental Intra-abdominal Klebsiella pneumoniae Infection in Mice.
Zheng M, Horne W, McAleer JP, Pociask D, Eddens T, Good M, Gao B, Kolls JK.
Infect Immun. 2016 Jan 4;84(3):782-9. doi: 10.1128/IAI.01268-15.

Pulmonary Th17 Antifungal Immunity Is Regulated by the Gut Microbiome.
McAleer JP, Nguyen NL, Chen K, Kumar P, Ricks DM, Binnie M, Armentrout RA, Pociask DA, Hein A, Yu A, Vikram A, Bibby K, Umesaki Y, Rivera A, Sheppard D, Ouyang W, Hooper LV, Kolls JK.
J Immunol. 2016 Jul 1;197(1):97-107. doi: 10.4049/jimmunol.1502566. Epub 2016 May 23.

Interleukin-22 Signaling in the Regulation of Intestinal Health and Disease.
Parks OB, Pociask DA, Hodzic Z, Kolls JK, Good M.
Front Cell Dev Biol. 2016 Jan 13;3:85. doi: 10.3389/fcell.2015.00085. eCollection 2015. Review.

A Novel CD4+ T-cell Dependent Murine Model of Pneumocystis Driven Asthma-like Pathology.
Eddens T, Campfield BT, Serody K, Manni ML, Horne W, Elsegeiny W, McHugh KJ, Pociask D, Chen K, Zheng M, Alcorn JF, Wenzel S, Kolls JK.
Am J Respir Crit Care Med. 2016 Mar 23. [Epub ahead of print]

Latent Expression of the Epstein-Barr Virus (EBV)-Encoded Major Histocompatibility Complex Class I TAP Inhibitor, BNLF2a, in EBV-Positive Gastric Carcinomas.
Strong MJ, Laskow T, Nakhoul H, Blanchard E, Liu Y, Wang X, Baddoo M, Lin Z, Yin Q, Flemington EK.
J Virol. 2015 Oct;89(19):10110-4. doi: 10.1128/JVI.01110-15. Epub 2015 Jul 15.

Analysis of Expression and Functions of Histone Deacetylase 6 (HDAC6).
Li M, Zhuang Y, Shan B.
Methods Mol Biol. 2016;1436:85-94. doi: 10.1007/978-1-4939-3667-0_6.

Prediction of improvement in skin fibrosis in diffuse cutaneous systemic sclerosis: a EUSTAR analysis.
Dobrota R, Maurer B, Graf N, Jordan S, Mihai C, Kowal-Bielecka O, Allanore Y, Distler O; EUSTAR coauthors (Saketkoo, LA).
Ann Rheum Dis. 2016 Mar 25. pii: annrheumdis-2015-208024. doi: 10.1136/annrheumdis-2015-208024. [Epub ahead of print]

Serum Jo-1 Autoantibody and Isolated Arthritis in the Antisynthetase Syndrome: Review of the Literature and Report of the Experience of AENEAS Collaborative Group.
Cavagna L, Nuño L, Scirè CA, Govoni M, Longo FJ, Franceschini F, Neri R, Castañeda S, Sifuentes Giraldo WA, Caporali R, Iannone F, Fusaro E, Paolazzi G, Pellerito R, Schwarting A, Saketkoo LA, Ortego-Centeno N, Quartuccio L, Bartoloni E, Specker C, Pina Murcia T, La Corte R, Furini F, Foschi V, Bachiller Corral J, Airò P, Cavazzana I, Martínez-Barrio J, Hinojosa M, Giannini M, Barsotti S, Menke J, Triantafyllias K, Vitetta R, Russo A, Bogliolo L, Bajocchi G, Bravi E, Barausse G, Bortolotti R, Selmi C, Parisi S, Salaffi F, Montecucco C, González-Gay MA; AENEAS (American and European NEtwork of Antisynthetase Syndrome) Collaborative Group.
Clin Rev Allergy Immunol. 2016 Jan 19. [Epub ahead of print]

Manual Aspiration Thrombectomy in Acute Myocardial Infarction: A Clinical Experience.
Jaiswal A, Pollack S, Chichra A, Moustakakis E, Park C, Kerwin T.
Int J Angiol. 2016 Mar;25(1):20-8.

Challenges in the Management of Patients with Chronic Obstructive Pulmonary Disease and Heart Failure With Reduced Ejection Fraction.
Jaiswal A, Chichra A, Nguyen VQ, Gadiraju TV, Le Jemtel TH.
Curr Heart Fail Rep. 2016 Feb;13(1):30-6

Assessing productive efficiency and operating scale of community blood centers.
Nielsen AE, Nielsen ND.
Transfusion. 2016 Jun;56(6):1267-73

Therapeutic bronchoscopy improves spirometry, quality of life, and survival in central airway obstruction.
Mahmood K, Wahidi MM, Thomas S, Argento AC, Ninan NA, Smathers EC, Shofer SL.
Respiration. 2015;89(5):404-13.

A Novel, Adaptable Laryngeal Mask to Facilitate a Percutaneous Dilatational Tracheostomy: Proof-of-Concept Prototype Demonstration on a Mannequin Model and Cadaver.
Vignes SM, Cover CG, Chedid NR, Kleinpeter SM, Palomino J.
J Bronchology Interv Pulmonol. 2015 Oct;22(4):319-25.

A Bronchial Genomic Classifier for the Diagnostic Evaluation of Lung Cancer.
Silvestri GA, Vachani A, Whitney D, Elashoff M, Porta Smith K, Ferguson JS, Parsons E, Mitra N, Brody J, Lenburg ME, Spira A; AEGIS Study Team (Collaborator: Palomino J).
N Engl J Med. 2015 Jul 16;373(3):243-51. Epub 2015 May 17.

Aberrant expression and activity of histone deacetylases in sporadic idiopathic pulmonary fibrosis.
Korfei M, Skwarna S, Henneke I, MacKenzie B, Klymenko O, Saito S, Ruppert C, von der Beck D, Mahavadi P, Klepetko W, Bellusci S, Crestani B, Pullamsetti SS, Fink L, Seeger W, Krämer OH, Guenther A.
Thorax. 2015 Nov;70(11):1022-32. Epub 2015 Sep 10.

Clinical trials in pulmonary sarcoidosis.
Baughman RP, Lower EE, Saketkoo LA.
Curr Opin Pulm Med. 2015 Sep;21(5):525-31.

Clinical Spectrum Time Course in Anti Jo-1 Positive Antisynthetase Syndrome: Results From an International Retrospective Multicenter Study.
Cavagna L, Nuño L, Scirè CA, Govoni M, Longo FJ, Franceschini F, Neri R, Castañeda S, Giraldo WA, Caporali R, Iannone F, Fusaro E, Paolazzi G, Pellerito R, Schwarting A, Saketkoo LA, Ortego-Centeno N, Quartuccio L, Bartoloni E, Specker C, Murcia TP, La Corte R, Furini F, Foschi V, Corral JB, Airò P, Cavazzana I, Martínez-Barrio J, Hinojosa M, Giannini M, Barsotti S, Menke J, Triantafyllias K, Vitetta R, Russo A, Bajocchi G, Bravi E, Barausse G, Bortolotti R, Selmi C, Parisi S, Montecucco C, González-Gay MA; AENEAS (American, European NEtwork of Antisynthetase Syndrome) collaborative group.
Medicine (Baltimore). 2015 Aug;94(32):e1144.

Association between Initial Oral Therapy and Outcomes in Systemic Sclerosis-related Pulmonary Arterial Hypertension: Observations from PHAROS.
Lammi MR, Mathai SC, Saketkoo LA, Domsic RT, Bojanowski C, Furst D, Steen V; PHAROS Investigators.
Arthritis Rheumatol. 2015 Oct 19. [Epub ahead of print]

Patient Perspectives in OMERACT Provide an Anchor for Future Metric Development and Improved Approaches to Healthcare Delivery in Connective Tissue Disease Related Interstitial Lung Disease (CTD-ILD).
Mittoo S, Frankel S, LeSage D, Strand V, Shah AA, Christopher-Stine L, Danoff S, Hummers LK, Swigris JJ, Huscher D, Christensen AM, Cenac SL, Erbil JK, Ferguson S, Garcia-Valladares I, Grewal HK, Orbai AM, Smith KC, Tran M, Bingham CO 3rd, Castelino FV, Fischer A, Saketkoo LA.
Curr Respir Med Rev. 2015 Jun;11(2):175-183.

Methylation status and AP1 elements are involved in EBV-mediated miR-155 expression in EBV positive lymphoma cells.
Yin Q, Wang X, Roberts C, Flemington EK, Lasky JA.
Virology. 2016 Jul.

Safety, tolerability and appropriate use of nintedanib in idiopathic pulmonary fibrosis.
Corte T, Bonella F, Crestani B, Demedts MG, Richeldi L, Coeck C, Pelling K, Quaresma M, Lasky JA.
Respir Res. 2015 Sep.

Outcome Measures for Clinical Trials in Interstitial Lung Diseases.
Lammi MR, Baughman RP, Birring SS, Russell AM, Ryu JH, Scholand M, Distler O, LeSage D, Sarver C, Antoniou K, Highland KB, Kowal-Bielecka O, Lasky JA, Wells AU, Saketkoo LA.
Curr Respir Med Rev. 2015;11(2):163-174.

Idiopathic Pulmonary Fibrosis in United States Automated Claims. Incidence, Prevalence, and Algorithm Validation.
Esposito DB, Lanes S, Donneyong M, Holick CN, Lasky JA, Lederer D, Nathan SD, O'Quinn S, Parker J, Tran TN.
Am J Respir Crit Care Med. 2015 Nov 15;192(10):1200-7.

Concurrent Intrapleural Instillation of Tissue Plasminogen Activator and Deoxyribonuclease for Pleural Infection: A Single Center Experience.
Majid A*, Kheir F*, Folch A, Fernandez-Bussy S,  Chatterji S, Maskey A,  Fashjian M,  Cheng G,  Ochoa S,  Alape D, Folch E.
Ann Am Thorac Soc. 2016 (In Press). * Both authors contributed equally for the preparation of this manuscript.

Epidemiology, Patterns of Care, and Mortality for Patients with Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries.
Bellani G, Laffey JG, Pham T, Fan E, Brochard L, Esteban A, Gattinoni L, van Haren F, Larsson A, McAuley DF, Ranieri M, Rubenfeld G, Thompson BT, Wrigge H, Slutsky AS, Pesenti A; LUNG SAFE Investigators (Kheir, F); ESICM Trials Group.
JAMA. 2016 Feb.

Biologic therapies in the treatment of sarcoidosis.
Saketkoo LA, Baughman RP. Expert Rev Clin Immunol.
2016 May 3:1-9. [Epub ahead of print]

Tunneled pleural catheter placement with and without talc poudrage for treatment of pleural effusions due to congestive heart failure.
Majid A, Kheir F, Fashjian M, Chatterji S, Fernandez-Bussy S, Ochoa S, Cheng G, Folch E .
Ann Am Thorac Soc.  2015 Nov.

Using Ultrasound Guided Peripheral Catheterization of the Internal Jugular Vein in Patients with Difficult Peripheral Access.
Butterfield M, Abdelghani R, Mohamad M, Limsuwat C, Kheir F.
Am J Ther. 2015 Oct.

Using Simulation-Based Training to Incorporate Thoracic Ultrasound into Physical Examination.
Eissa K, Alokla K, Assasa O, Itani A, Shawwa K, Kheir F.
J La State Med Soc. 2015 Nov-Dec.

The Role of Sedation in Endobronchial Ultrasound-guided Transbronchial Needle Aspiration: Systematic Review.
Aswanetmanee P, Limsuwat C, Kabach M, Alraiyes A, Kheir F.
Endosc Ultrasound 2016 (In Press)

The Utility of Endobronchial Ultrasound-Transbronchial Needle Aspiration in Lymphoma.
Kheir F, Itani A, Assasa O, Alraiyes A.
Endosc Ultrasound 2016; 5 (1):43-8.

Medical Thoracoscopy: Technique and Application.
Alraiyes A,  Dhillon  S, Harris K, Kaphle U, Kheir F.
PLEURA January-December 2016.

Manometry in Pleural Drainage: Essential Practice or Over-Rated Gadget?
Kheir F, Maldonado F.
Curr Pulmonol Rep .March 2016, Volume 5, Issue 1, pp 7-12.

39-Year- Old Female with Mild Respiratory distress and Hypoxia.
Okoye O, Daroca PJ, Kaphle U, Kheir F, Salerno D.
J La State Med Soc. 2016 Jan-Feb; 168(1):2-5.

The Undefined Value of Pleural Interventions in Advanced Heart Failure and Recurrent Pleural Effusions-Reply.
Majid A, Kheir F, Fashjian M, Chatterji S, Fernandez-Bussy S, Ochoa S, Cheng G, Folch E .
Ann Am Thorac Soc. Vol. 13, No. 3, March 1, 2016: 448-449.

Successful Use of the "Peripheral IJ".
Butterfield M, Limsuwat C, Haynes J, Kheir F.
J Emerg Med. 2016 Feb; 50(2):e69-70.

Cigarette smoke represses the innate immune response to asbestos.
Morris, G. F., S. Danchuk, Y. Wang, B. Xu, R. J. Rando, A. R. Brody, B. Shan and D. E. Sullivan
(2015). Physiol Rep 3(12).

Deregulation of selective autophagy during aging and pulmonary fibrosis: the role of TGFβ1.
Sosulski ML, Gongora R, Danchuk S, Dong C, Luo F, Sanchez CG.
Aging Cell. 2015 Oct;14(5). Epub 2015 Jun.

Regulation of transforming growth factor-beta1 (TGF-β1)-induced pro-fibrotic activities by circadian clock gene BMAL1.
Dong C, Gongora R, Sosulski ML, Luo F, Sanchez CG.
Respir Res. 2016 Jan.

Involvement of Interleukin-18 in the pathogenesis of human eosinophilic esophagitis.
Rituraj Niranjan, Priya Rajavelu, Jai Shankar Shukla,1 Asifa Zaidi, Siddesha Jalahalli Mariswamy, Jochen Mattner, Ilana Fortgang, Monika Kowalczyk, Luis Balart, Anshi Shukla, and Anil Mishra.
Clinical Immunology, 2015.

Allergen-induced Interleukin-18 promotes experimental eosinophilic esophagitis in mice.
Parmesh Dutt, Jai Shankar Shukla, Sathisha Upparahalli Ventateshaiah, Siddesha Jalahalli. Mariswamy, Jochen Mattner, Anshi Shukla and Anil Mishra.
Immunology and Cell Biology 2015 Nov 24.

Food allergy and eosinophilic esophagitis in India: Lack of diagnosis.
Niranjan R, Thakur, AK and Mishra, A.
Indian J Gastroenterol. Published Online Feb 13, 2016.

Potential of inducible Nitric Oxide synthase as a therapeutic target for allergen-induced airway hyperresponsiveness: A critical connection to Nitric Oxide levels and PARP activity  "
Salome Ibba, Mohamed Ghonim, Kusma Pyakurel, Matthew Lammi, Anil Mishra and Hamid Boulares.
Mediators of Inflammation, 2016. (In Press.)

Factors Associated With Reintubation in Patients With Chronic Obstructive Pulmonary Disease.
Nantsupawat N, Nantsupawat T, Limsuwat C, Sutamtewagul G, Nugent K.
Qual Manag Health Care. 2015 Oct-Dec;24(4)

Medical Thoracoscopy Technique and Application.
Alraiyes A, Dhillon S, Harris K, Kaphle U, Kheir F.
Pleura (March, 2016)

The pH-Glucose Relationship in Malignant Pleural Effusion.
Kheir F, Alraiyes A, Kaphle U, Ahmed F.
Journal of Bronchology and Interventional Pulmonology (April, 2016)

The Idiopathic Pulmonary Fibrosis Clinical Research Network (IPFnet): diagnostic and adjudication processes.
de Andrade J, Schwarz M, Collard HR, Gentry-Bumpass T, Colby T, Lynch D, Kaner RJ; IPFnet Investigators (Lasky collaborator).
Chest. 2015 Oct;148(4):1034-42. doi: 10.1378/chest.14-2889.

Book Chapters, Abstracts and Poster Presentations

A Rare Case of ARDS from Human Anaplasmosis.
Kaphle U, Kheir F, Thammasitboon S.
Respiratory Care (July, 2015)


A 45-Year-Old Woman With 3 Weeks of Cough and Night Sweats.
Than Htaik Kyaw; Lacey Sullivan; and Ross C. Klingsberg.
CHEST [149, 3], 2016 Mar.


B-Cell Depletion Salvage Therapy in Rapidly Progessive Dermatomyositis Related Interstitial Lung Disease.
Eissa K, Palomino J.
J La State Med Soc. 2016 June;168:99-100


Book Chapter: Autophagy and Metabolism.
Jaime L. Schneider and Cecilia G. Sanchez.
DOI: 10.1142/9789814635011_0019 In Book: The Aging lungs. Mechanisms and Clinical Sequelae.


Book Chapter: Aging in COPD and Idiopathic Pulmonary Fibrosis.
Cecilia G. Sanchez.
December 2015. DOI: 10.1007/978-3-319-23246-1_15 In book: Advances in Geroscience, pp.429-470.


Book Chapter: Care of the Adult with Cystic Fibrosis”
Klingsberg R, Landry M
In Book: Care of the Adult with a Chronic Childhood Condition: A Practical Guide
Editors: David DeLaet, Alice Kuo, Cynthia Peacock, Mariecel Pilapil, and Niraj Sharma.
Spinger 2016


Concise Clinical Appraisal: High Flow oxygen in low risk for intubation patients.
Chaudhari P, Kaphle U, Nielsen N.
Critical eConnections (June, 2016)


Concise Clinical Appraisal: High vs Low BP targets in patients with shock.
Limsuwat C, Kaphle U, Nielsen N.
Critical eConnections (May, 2016)


Clinical Appraisal: The predictor power of Mitochondrial DNA and Toll-Like Receptor-9.
Okoye O, Kaphle U, Nielsen, N.
Critical eConnections (March 2, 2016)


Concise Clinical Appraisal: Rapid Diagnosis of Infection in Critically Ill.
Kaphle U, Nielsen N.
Critical eConnections (Feb 3, 2016)



July 2014 - June 2015

Faculty Publications

Serum and bal beta-D-glucan for the diagnosis of Pneumocystis pneumonia in HIV positive patients.
Salerno D, Mushatt D, Myers L, Zhuang Y, de la Rua N, Calderon EJ, Welsh D.
Respir Med. 2014 Nov;108(11):1688-95.
PMID: 25448310

A 24-Hour Postintensive Care Unit Transition-of-Care Model Shortens Hospital Stay.
Kheir F, Shawwa K, Nguyen D, Alraiyes A, Simeone F, Nielsen N.
J Intensive Care Med. 2015 Jan 30. pii: 0885066615569701.
PMID: 25636643

Tunneled Pleural Catheter for the Treatment of Malignant Pleural Effusion: A Systematic Review and Meta-analysis.
Kheir F, Shawwa K, Alokla K, Omballi M, Alraiyes AH.
Am J Ther. 2015 Feb 2.
PMID: 25654292

Value of Endobronchial Ultrasound Transbronchial Needle Aspiration in Normal Positron Emission Tomography in Lung Cancer.
Aloka K, Kheir F, Palomino J.
J Bronchology Interv Pulmonol. 2015 Jan;22(1):e1-2.
PMID: 25590493

lincRNA HOTAIR as a novel promoter of cancer progression.
Loewen G, Zhuo Y, Zhuang Y, Jayawickramarajah J, Shan B.
J Can Res Updates. 2014 Jul;3(3):134-140.
PMID: 25663954

Elevated expression of long intergenic non-coding RNA HOTAIR in a basal-like variant of MCF-7 breast cancer cells.
Zhuang Y, Nguyen HT, Burow ME, Zhuo Y, El-Dahr SS, Yao X, Cao S, Flemington EK, Nephew KP, Fang F, Collins-Burow B, Rhodes LV, Yu Q, Jayawickramarajah J, Shan B.
Mol Carcinog. 2014 Oct 18. doi: 10.1002/mc.22237. [Epub ahead of print]
PMID: 25328122

Allergen-Induced Resistin-like molecule-a promotes esophageal epithelial cell hyperplasia in eosinophilic esophagitis.
Mavi P, Crump CH, Niranjan R, Dutt P, Zaidi A, Shukla JS, Korfhagen T, Mishra A.
Am J Physiol Gastrointest Liver Physiol. 2014 Sep 1;307(5): G499-G507.
PMID: 24994859

Diagnostic and therapeutic strategies for eosinophilic esophagitis.
Zaidi AK, Mussarat A, Mishra A.
Clin Pract (Lond). 2014;11(3):351-367.
PMID: 25400904

Involvement of interleukin-18 in the pathogenesis of human esosinophilic esophagitis.
Niranjan R, Rajavelu P, Ventateshaiah SU, Shukla JS, Zaidi A, Mariswamy SJ, Mattner J, Fortgang I, Kowalczyk M, Balart L, Shukla A, Mishra A.
Clin Immunol. 2015 Jan 28;157(2):103-113.
PMID: 25638412

Allergen-induced interleukin-18 promotes experimental eosinophilic oesophagitis in mice.
Dutt P, Shukla JS, Ventateshaiah SU, Mariswamy SJ, Mattner J, Shukla A, Mishra A.
Immunology and Cell Biology 2015 Mar 24.
PMID: 25801352

Therapeutic Bronchoscopy Improves Spirometry, Quality of Life, and Survival in Central Airway Obstruction.
Mahmood K, Wahidi MM, Thomas S, Argento AC, Ninan NA, Smathers EC, Shofer SL.
Respiration. 2015 Apr 23. [Epub ahead of print]
PMID: 25925488

The Utility of Endobronchial Ultrasound-Transbronchial Needle Aspiration in Lymphoma.
Kheir F, Itani A, Assasa O, Alraiyes A.
Endosc Ultrasound. (In press)

Promotion of Lung Tumor Growth by Interleukin-17.
Xu B, Guenther JF, Pociask DA, Wang Y, Kolls JK, You Z, Chandrasekar B, Shan B, Sullivan DE, Morris GF.
Am J Physiol Lung Cell Mol Physiol. 2014 Sep 15;307(6):L497-508. Epub 2014 Jul 18.
PMID: 25038189

Should Endobronchial Ultrasound be Performed in All Patients with Suspected Sarcoidosis?
Assasa O, Omballi M, Kheir F.
Intl J Resp & Pulm Med. 2014, 1:1.
ISSN: 2378-3516

Endobronchial ultrasound in a patient with right aortic arch.
Alraiyes AH, Alokla K, Kheir F, Palomino J.
Ochsner J. 2014 Summer;14(2):279-81.
PMID: 24940143

Biotechnological drugs: the breakthrough in autoimmune rheumatic conditions.
Cavagna L, Saketkoo LA, Schwarting A, Caporali R.
Biomed Res Int. 2014;2014:481973. Epub 2014 Aug 10.
PMID: 25180183

A Comparison of Two Laboratories for the Measurement of Wood Dust Using Button Sampler and Diffuse Reflection Infrared Fourier-Transform Spectroscopy (DRIFTS).
Chirila MM, Sarkisian K, Andrew ME, Kwon CW, Rando RJ, Harper M.
Ann Occup Hyg. 2015 Apr;59(3):336-46. Epub 2014 Dec 2.
PMID: 25466763

Fluid Management with a Simplified Conservative Protocol for the Acute Respiratory Distress Syndrome.
Grissom CK, Hirshberg EL, Dickerson JB, Brown SM, Lanspa MJ, Liu KD, Schoenfeld D, Tidswell M, Hite RD, Rock P, Miller RR 3rd, Morris AH; National Heart Lung and Blood Institute Acute Respiratory Distress Syndrome Clinical Trials Network (Simeone J, collaborator).
Crit Care Med. 2015 Feb;43(2):288-95.
PMID: 25599463

Personalized contact strategies and predictors of time to survey completion: analysis of two sequential randomized trials.
Dinglas V, Huang M, Sepulveda K, Pinedo M, Hopkins R, Colantuoni E, Needham, NIH NHLBI ARDS Network (Simeone J, collaborator).
BMC Med Res Methodol. 2015 Jan 9;15:5. doi: 10.1186/1471-2288-15-5.
PMID: 25575599

Treatment of Recurrent Non-Malignant Pleural Effusions.
Omballi M, Kheir F.
Austin J Pulm Respir Med. 2014;1(4): 3.

Screening for Lung Cancer.
Kheir F, Eissa K, Palomino J.
J Cancer Biol Res 2014; 2(1): 1023

Manometry in Pleural Drainage: Essential Practice or Over-Rated Gadget?
Kheir F, Maldonado F.
Curr Pulmonol Rep (In progress)

Medical Thoracoscopy.
Alraiyes A, Kaphle U, Kheir F.
Pleura (In progress)

Broken Lung.
Klair I, Palomino J, Kheir F, Salerno D.
J La State Med Soc. 2014 Nov-Dec; 166(6)

A Rare Case of ARDS from Human Anaplasmosis.
Kaphle U, Kheir F, Thammasitboon S. Respir Care. 2015 Feb 10. pii: respcare.03714.
PMID: 25669216

Nutrition in Critically Ill Patients.
Assasa O, Kheir F.
Austin Crit Care J. 2014;1(1): 2.

Pulmonary rehabilitation improves only some domains of health-related quality of life measured by the Short Form-36 questionnaire.
Limsuwat C, McClellan R, Amiri HM, Nugent K.
Ann Thorac Med. 2014 Jul;9(3):144-8.
PMID: 24987472

The association between glucose levels and hospital outcomes in patients with acute exacerbations of chronic obstructive pulmonary disease.
Islam EA, Limsuwat C, Nantsupawat T, Berdine GG, Nugent KM.
Ann Thorac Med. 2015 Apr-Jun;10(2):94-9.
PMID: 25829959

Chiari Syndrome and Respiratory Failure: A Literature Review.
Kijsirichareanchai K, Limsuwat C, Mankongpaisarnrung C, Nantsupawat N, Nugent K.
J Intensive Care Med. 2014 Sep-Oct;29(5):260-8. Epub 2013 Apr 12.
PMID: 23753239

Factors Associated with Emergency Department Visits for Asthma Exacerbation.
Wells RE, Garb J, Fitzgerald J, Kleppel R, Rothberg M.
Southern Medical Journal. 2015; 108(5) 276-280.
PMID: 25972214

Functional Recovery in a Patient with Postanoxic Myoclonus Secondary to Anaphylactic Shock.
Kaphle U, Bailey R, Singh S,
Crit Care Med. 42(12):A1664, December 2014.

The “16 Hour Rule”. A Giant Step, But in Which Direction?
Popkin JH, Eissa K, Mazor K, Lemay C.
Am J Med. 2015 May 13. doi: 10.1016/j.amjmed.2015.04.022.
PMID: 25981692

Deregulation of selective autophagy during aging and pulmonary fibrosis. The role of TGFß1.
Sosulski ML, Gongora R, Danchuk S, Dong C, Luo F, Sanchez CG.
Aging Cell. 2015. (In press)

Using Simulation-Based Training to Incorporate Thoracic Ultrasound into Physical Examination.
Eissa K, Alokla K, Assasa O, Itani A, Shawwa K, Kheir F.
J La State Med Soc. (In Press)

Case Report: 39 year old female with mild respiratory distress and hypoxia.
Okoye O, Daroca P, Kaphle U, Kheir F, Salerno D.
J LA State Medical Society. (In press)

Book Chapters, Abstracts and Poster Presentations

Lung Neoplasms. In: ATS Review for the Pulmonary Boards.
American Thoracic Society; 2014.
Eds. Le T, Khosa S, Pasnick S, Wang T, Cherian VC, Kheir F., Palomino J, Senior Reviewer.
New York, NY; 2015:515-564.

Maintenance of Certification Education Module on Severe Asthma.
Thomson CC, Arunachalam A, Le T, Chima-Okereke C, Kheir F, Patel D, Brozek J, Chung F, Gibson P,
Wilson K, Larsson E, Siegel-Gasiewski J, Wenzel S, Welsh C.
American Thoracic Society [Approved by the ABIM], 2014 [Approved through 2017].

Innovative Clinical Research Certificate for Pulmonary and Critical Medicine Fellowship Trainees.
Kheir F, Palomino J.
2015 ATS Innovations in Fellowship Education Program.
ATS 2015 International Conference.

The 16 Hour Rule”: a Giant Step, But in Which Direction
Eissa K, Popkin J, Mazor K, Lemay C.
ATS 2015 meeting. May 2015, Denver, CO.

B-Cell Depletion Salvage Therapy in Rapidly Progressive Dermatomyositis Related Interstitial Lung Disease.
Eissa K, Palomino J.
Chest 2014 meeting. October 2014, Austin TX.


July 2013 - June 2014

Basic Science Original Manuscripts

Effect of Flow Trigger on Rapid Shallow Breathing Index (RSBI) Measured Through the Ventilator.
Kheir F, Myers L, Desai N, Simeone F.
Journal of Intensive Care Medicine, 2013 Sep 24. PMID: 24067546

Screening for Lung Cancer.
Kheir F, Eissa K, Palomino J.
J Cancer Biol Res. 2014; 2(1): 1023.

Diagnosing diagnostic error.
Thammasitboon S, Thammasitboon S, Singhal G.
Curr Probl Pediatr Adolesc Health Care. 2013 Oct;43(9):227-31. PMID: 24070579

System-related factors contributing to diagnostic errors.
Thammasitboon S, Thammasitboon S, Singhal G.
Curr Probl Pediatr Adolesc Health Care. 2013 Oct;43(9):242-7. PMID: 24070581

Endobronchial Ultrasound-Transbronchial Needle Aspiration of Mediastinal and Hilar Lymphadenopathy Learning Curve.
Kheir F, Alokla K, Myers L, Palomino J.
Am J Ther. 2014 Mar 10. PMID: 24621644

Giant Saphenous Vein Coronary Artery Bypass Graft Aneurysm.
Klair I, Palomino J.
Am J Respir Crit Care Med. 2014 Mar 1;189(5):e8-9. PMID: 24579843

The placental specific gene, PLAC1, is induced by the Epstein-Barr virus and is expressed in human tumor cells.
Wang, X, Baddoo MC, Yin Q.
Virology Journal 2014, 11:107, Jun 9. doi: 10.1186/1743-422X-11-107 PMID: 24912876

Exposures to Thoracic Particulate Matter, Endotoxin, and Glucan During Post-Hurricane Katrina Restoration Work, New Orleans 2005 – 2012.
Rando RJ, Kwon CW, Lefante JJ.
J. Occup. Environ. Hyg. 2014; 11(1):9-18, 2014. PMID: 24283332

Activation of Aryl Hydrocarbon Receptor Signaling by Extracts of Teak and Other Wood Dusts.
Wilson MJ, Rando RJ, Sabbioni G, Miller CA.  
Environ Toxicol. 2014 Jun 5. doi: 10.1002/tox.22007, 2014. PMID: 24898320

Significance of mouse models in dissecting the mechanism of human eosinophilic gastrointestinal diseases (EGD).
Mishra A.
J Gastroenterology and Hepatology; Dec. 2013; 2(11), 845-853.

Invariant natural killer T cells neutralization is a possible novel therapy for human eosinophilic esophagitis.
Madhavi, R, Rajavelu P. Zhu Z, Kaul A, Niranjan R, Dyna S, Mishra A, Mattner J, Zaidi A, Dutt P, Mishra A.  
Clinical and Translational Immunology, 2014: 3, 1-11.

Resistin-like molecule (Relm)-α induction in eosinophilic esophagitis promotes esophageal epithelial cell hyperplasia.
Mavi P, Crump CH, Niranjan R, Dutt P, Zaidi A, Shukla  JS, Korfhagen T, Mishra A.
AJP-Gastroentrology. Published online June 7, 2014.

Detecting splicing variants in idiopathic pulmonary fibrosis from non-differentially expressed genes.
Deng N, Sanchez CG, Lasky JA, Zhu D.
PLoS One. 2013 Jul 2;8(7):e68352. doi: 10.1371/journal.pone.0068352. Print 2013. PMID: 23844188
 
Arsenic trioxide inhibits TGF-β1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo.
Luo F, Zhuang Y, Sides MD, Sanchez CG, Shan B, White ES, Lasky JA.
Respir Res. 2014 Apr 24;15(1):51. PMID: 24762191

Interleukin 6 mediates the therapeutic effects of adipose-derived stromal/stem cells in lipopolysaccharide-induced acute lung injury.
Zhang S, Danchuk SD, Bonvillain RW, Xu B, Scruggs BA, Strong AL, Semon JA, Gimble JM, Betancourt AM, Sullivan DE, Bunnell BA.
Stem Cells. 2014 Jun;32(6):1616-28. doi: 10.1002/stem.1632. PMID: 24449042

The tyrosine kinase inhibitor imatinib has potent vasodilator activity in the pulmonary and systemic vascular beds in the rat.
Pankey EA, Lasker GF, Thammasitboon S, Babar S, Lasky JA, Kadowitz. PJ.
Am J Physiol Heart Circ Physiol. 2013 Nov 1;305(9):H1288-96. PMID: 23997103

Randomized trial of acetylcysteine in idiopathic pulmonary fibrosis.
Idiopathic Pulmonary Fibrosis Clinical Research Network (Lasky JA, collaborator), Martinez FJ, de Andrade JA, Anstrom KJ, King TE Jr, Raghu G. (Lasky JA, collaborator).
N Engl J Med. 2014 May 29;370(22):2093-101. PMID: 24836309

Efficacy and safety of nintedanib in idiopathic pulmonary fibrosis.
Richeldi L, du Bois RM, Raghu G, Azuma A, Brown KK, Costabel U, Cottin V, Flaherty KR, Hansell DM, Inoue Y, Kim DS, Kolb M, Nicholson AG, Noble PW, Selman M, Taniguchi H, Brun M, Le Maulf F, Girard M, Stowasser S, Schlenker-Herceg R, Disse B, Collard HR; INPULSIS Trial Investigators (Lasky JA, collaborator).
N Engl J Med. 2014 May 29;370(22):2071-82. PMID: 24836310

A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis.
King TE Jr, Bradford WZ, Castro-Bernardini S, Fagan EA, Glaspole I, Glassberg MK, Gorina E, Hopkins PM, Kardatzke D, Lancaster L, Lederer DJ, Nathan SD, Pereira CA, Sahn SA, Sussman R, Swigris JJ, Noble PW; ASCEND Study Group (Lasky JA, collaborator).
N Engl J Med. 2014 May 29;370(22):2083-92. PMID: 24836312

Incidence and Predictors of Vancomycin Associated Nephrotoxicity.
Moh’d H, Kheir F, Lan K. Du P, Farag H, Mohamad A, Zurlo J.
South Med J 2014 June;107(6):383-388. PMID: 24945176

Diagnostic and therapeutic strategies for eosinophilic esophagitis.  
Zaidi A, Mishra A. 2014. 
Future Medicine. 2014, In Press.

Pathogenesis of allergen-induced eosinophilic esophagitis is independent of interleukin (IL)-13. 
Niranjan R, Rayapudi M, Mishra A, Dutt P, Dynda S, Mishra A.
Immunol Cell Biol. 2013 Jul:91(6):408-15. doi: 10.1038/icb.2013.21. PMID: 23689305

Effects of implementing a protocol for arterial blood gas use on ordering practices and diagnostic yield.
DellaVolpe J, Chakraborti C, Cerreta K, Romero C, Firestein C, Meyers L, Nielsen N.
Healthcare 2 (2014)130-135.

Case Reports, Editorials and Presentations

Late presentation of lung sequestration.
Alokla K, Alraiyes AH, Alraies MC.
BMJ Case Rep. 2013 Aug 30;2013. PMID: 23997084

Lung air-fluid level in a smoker.
Kheir F, Alraiyes AH, Salerno D, Alraies MC.
Cleve Clin J Med. 2013 Aug;80(8):500-1. PMID: 23908106

Brain Natriuretic Peptide Measurement in Patients With COPD and Cardiovascular Disease.
Kheir F, Salerno D.
Chest. 2013 Sep; 144(3):1081. PMID: 24008964

Phenytoin-Associated Granulamatous Pulmonary Vasculitis.
Kheir F, Daroca P, Lasky J.
Amer J Ther. 2013 Nov 15. PMID: 24247101

Pulmonary Artery Catheter Placement Guided by Echocardiography.
Alraies MC, Alraiyes AH, Salerno D.
QJM. 2013 Dec;106(12):1149-50. doi: 10.1093/qjmed/hcs215. Epub 2012 Nov 5. PMID: 23132951

CNS Complications in Pulmonary Arteriovenous Malformations.
Salerno D.
Chest 2014; 145(2)426. PMID: 24493536

Endobronchial Ultrasound In A Patient With Right Aortic Arch.
Alraiyes A, Alokla K, Kheir F, Palomino J.
The Ochsner J.14:240-243, 2014. PMID: 24940143

Spontaneous Epidural Air Entrapment.
Eisa N, Moh’d H, Alraiyes A, Shaheen K, Kheir F
The Ochsner J. 14:279-281, 2014. PMID: 24940134

Suspected acute exacerbation of idiopathic pulmonary fibrosis as an outcome measure in clinical trials.
Collard HR, Yow E, Richeldi L, Anstrom KJ, Glazer C; IPFnet investigators (Lasky JA, collaborator).
Respir Res. 2013 Jul 13;14:73. PMID: 23848435

Reconciling Healthcare Professional and Patient Perspectives in the Development of Disease Activity and Response Criteria in Connective Tissue Disease-related Interstitial Lung Diseases.
Saketkoo LA, Mittoo S, Frankel S, Lesage D, Sarver C, Phillips K, Strand V, Matteson EL; OMERACT Connective Tissue Disease–Interstitial Lung Diseases Working Group; Delphi Process Collaborators (Klingsberg RC, Lasky JA, collaborators).
J Rheumatol. 2014 Apr;41(4):792-8. PMID: 24488412

Connective tissue disease related interstitial lung diseases and idiopathic pulmonary fibrosis: provisional core sets of domains and instruments for use in clinical trials.
Saketkoo LA, Mittoo S, Huscher D, Khanna D, Dellaripa PF, Distler O, Flaherty KR, Frankel S, Oddis CV, Denton CP, Fischer A, et al. Delphi Collaborators (Klingsberg RC, Lasky JA, collaborators).
Thorax. 2014 May;69(5):436-444. PMID: 24368713

Diagnostic Error.  In: Patient Safety - A Case-Based Comprehensive Guide
Ed. Abha Agrawal
Thammasitboon S, Thammasitboon S, Singhal G.
Springer New York, 2014, pp.231-245. ISBN; 9781461474180 (print), 9781461474197 (online)

Anaphylaxis. In: Manual of Intensive Care Medicine. 6th edition.
Eds.  Richard S. Irwin MD, James M Rippe MD.
Hollingsworth HM, Parada NA.
Lippincott Williams, 2014, p.140. ISBN: 9781451185003

Meningitis-Retention Syndrome as a Presentation of West Nile Virus Meningitis.
Mankongpaisarnrung C, Laengvejkal P, Argueta E, Limsuwat C, Sutamtewagul G, Nugent K.
Case Rep Med. 2013;2013:984345. Epub 2013 Jul 31. PMID: 23983716

Cholestatic jaundice as a result of combination designer supplement ingestion.
Vilella AL, Limsuwat C, Williams DR, Seifert CF.
Ann Pharmacother. 2013 Jul-Aug;45(7-8):e33. PMID: 23757384

Factors influencing the length of hospital stay in patients with acute exacerbations of chronic obstructive pulmonary disease admitted to intensive care units.
Limsuwat C, Mankongpaisarnrung C, Dumrongmongcolgul N, Nugent K.
Qual Manag Health Care. 2014 Apr-Jun;23(2):86-93. PMID: 24710184

COPD in older patients. In: Case Files Geriatrics. 1st edition.
Eds. Toy E, Dentino A, William M, Johnson L.
Limsuwat C, Subash M, Jumper C, Nugent K.
McGraw-Hill, 2014, pp. 71-81. ISBN10: 007177078X, ISBN13: 9780071770781

2012–2013 Academic Year Publications

Basic Science Original Manuscripts

Altered death receptor signaling promotes epithelial-to-mesenchymal transition and acquired chemoresistance.
Antoon JW, Lai R, Struckhoff AP, Nitschke AM, Elliott S, Martin EC, Rhodes LV, Yoon NS, Salvo VA, Shan B, Beckman BS, Nephew KP, Burow ME.
Sci Rep. 2012;2:539. PMID: 22844580

The microRNA expression associated with morphogenesis of breast cancer cells in three-dimensional organotypic culture.
Nguyen HT, Li C, Lin Z, Zhuang Y, Flemington EK, Burow ME, Lin Y, Shan B.
Oncol Rep. 2012 Jul;28(1):117-26. PMID: 22576799

Inhibition of chlorine-induced lung injury by the type 4 phosphodiesterase inhibitor rolipram.
Chang W, Chen J, Schlueter CF, Rando RJ, Pathak YV, Hoyle GW.
Toxicol Appl Pharmacol. 2012 Sep 1;263(2):251-8. PMID: 22763362

Circadian Gating of Epithelial-to-Mesenchymal Transition in Breast Cancer Cells Via Melatonin-Regulation of GSK3β
Mao L, Dauchy RT, Blask DE, Slakey LM, Xiang S, Yuan L, Dauchy EM, Shan B, Brainard GC, Hanifin JP, Frasch T, Duplessis TT, Hill SM.
Mol Endocrinol. 2012 Nov;26(11):1808-20.PMID: 23002080

Comparative profiling of miRNA expression of lung adenocarcinoma cells in two-dimensional and three-dimensional cultures.
Li C, Nguyen HT, Zhuang Y, Lin Z, Flemington EK, Zhuo Y, Kantrow SP, Morris GF, Sullivan DE, Shan B.
Gene. 2012 Dec 15;511(2):143-50. PMID: 23036707

Src-mediated morphology transition of lung cancer cells in three-dimensional organotypic culture.
Nguyen HT, Zhuang Y, Sun L, Kantrow SP, Kolls JK, You Z, Zhuo Y, Shan B.
Cancer Cell Int. 2013 Feb 14;13(1):16. PMID: 23409704

Human Cytomegalovirus Infection Dysregulates the Wnt/b-Catenin Signaling Pathway in Human Cytotrophoblasts. Angelova M, Zwezdaryk K, Ferris MB, Shan B, Morris CA, And Sullivan DE. 
PLoS Pathog. 2012;8(10):e1002959. PubMed PMID: 23071438

Determination of airborne wood dust in Button samples by diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS).
Kwon CW, Chirila M, Lee T, Harper M, Rando RJ.
Int. J. Environ. Anal. Chem. Vol. 2013, 12 pages. doi:10.1080/03067319.2012.755619

Nelfinavir suppresses insulin signaling and nitric oxide production by human aortic endothelial cells: protective effects of thiazolidinediones.
Mondal D, Liu K, Hamblin M, Lasky JA, Agrawal KC.
Ochsner J. 2013 Spring;13(1):76-90. PMID: 23533049

Induction of long intergenic non-coding RNA HOTAIR in lung cancer cells by type I collagen.
Zhuang Y, Wang X, Nguyen HT, Zhuo Y, Cui X, Fewell C, Flemington EK, Shan B.
J Hematol Oncol. 2013 May 13;6:35. PMID: 23668363

Co-treatment with arsenic trioxide and ganciclovir reduces tumor volume in a murine xenograft model of nasopharyngeal carcinoma.
Sides MD, Sosulski ML, Luo F, Lin Z, Flemington EK, Lasky JA.
Virol J. 2013 May 16;10:152. PMID: 23680002

Overexpression of Sulf2 in idiopathic pulmonary fibrosis.
Yue X, Lu J, Auduong L, Sides MD, Lasky JA.
Glycobiology. 2013 Jun;23(6):709-19. PMID: 23418199

Detecting splicing variants in idiopathic pulmonary fibrosis from non-differentially expressed genes.
Deng N, Sanchez CG, Lasky JA, Zhu D.
PLoS One, in press.

Clinical Reports

Comparison of 3 different methods used to measure the rapid shallow breathing index.
Desai NR, Myers L, Simeone F.
J Crit Care. 2012 Aug;27(4):418.e1-6. PMID: 21958982

Critical Airway Management: A Suggested Modification to the Rigid Fiber-Optic Stylet Based on 301 Novice Intubations
Sangwan YS, Palomino J, Simeone F, Koveleskie J.
J Bronchology Intervent Pulmonol. 2012 Oct;19(4):349-357. PMID: 23207543

Endobronchial ultrasound transbronchial needle aspiration in mediastinal and hilar lymphadenopathies.
Kheir F, Palomino J.
South Med J. 2012 Dec;105(12):645-9. PMID: 23211498

Respiratory health effects associated with restoration work in post-Hurricane Katrina New Orleans.
Rando RJ, Lefante JJ, Freyder LM, Jones RN.
J Environmental and Public Health. November 2012. doi:10.1155/2012/462478462478. PMID: 23365586

Respiratory Health and Flood Restoration Work in the Post Katrina Environment.
Rando RJ, Lefante JJ, Freyder LM, Jones RN.
In Bioaerosols - 6th International Scientific Conference on Bioaerosols, Fungi, Bacteria, Mycotoxins in Indoor and Outdoor Environments and Human Health. 
Johanning E., Morey PR, Auger P; Eds. Albany, NY: Fungal Research Group Foundation, Inc., 2012. ISBN: 978-0-9709915-0-8

One year outcomes in patients with acute lung injury randomised to initial trophic or full enteral feeding: prospective follow-up of EDEN randomized trial.
Needham DM, Dinglas VD, Bienvenu OJ, Colantuoni E, Wozniak AW, Rice TW, Hopkins RO; NIH NHLBI ARDS Network (Simeone F, one of 195 collaborators).
BMJ. 2013 Mar 19;346:f1532. doi: 10.1136/bmj.f1532.PMID: 23512759

Pulmonary artery catheter placement guided by echocardiography.
Alraies MC, Alraiyes AH, Salerno D.
QJM. 2012 Nov 5. PMID: 23132951

A Practical Algorithmic Approach to the Diagnosis and Management of Solitary Pulmonary Nodules: Part 1: Radiologic Characteristics and Imaging Modalities
Patel VK, Naik SK, Naidich DP, Travis WD, Weingarten JA, Lazzaro R, Gutterman DD, Wentowski C, Grosu HB, Raoof S.
Chest. 2013 Mar 143(3):825-839. doi:10.1378/chest.12-0960 .PMID: 23460160

A Practical Algorithmic Approach to the Diagnosis and Management of Solitary Pulmonary Nodules: Part 2: Pretest Probability and Algorithm
Patel VK, Naik SK, Naidich DP, Travis WD, Weingarten JA, Lazzaro R, Gutterman DD, Wentowski C, Horiana B. Grosu HB, Raoof S.
Chest. 2013 Mar 143(3):840-846. doi:10.1378/chest.12-1487. PMID: 23460161

Role of Anemia in Home Oxygen Therapy in Chronic Obstructive Pulmonary Disease Patients.
Copur AS, Fulambarker A, Molnar J, Nadeem R, McCormack C, Ganesh A, Kheir F, Hamon S.
Am J Ther. 2013 Apr 5. PMID: 23567789

Case Reports

Alendronate Tracheobronchitis
Mahmood K, Koubar S, Shofer SL, Ninan NA, Wahidi MM.
Ann Am Thorac Soc. 2013 Feb;10(1):64-6. doi: 10.1513/AnnalsATS.201212-124OT.PMID: 23509337

A 40-year-old woman with multiple lung nodules.
Alraiyes AH, Kheir F, Hirsh S, Salerno D, Bernal-Green L, Daroca P.
Chest. 2013 Jun 1;143(6):1826-9. PMID: 23732596

Asymptomatic Lung Air-Fluid Level in a Smoker.
Kheir F, Alraiyes AH, Salerno D, Alraies MC.
Cleveland Clinic Journal of Medicine. Accepted September 2012.

Brain Natriuretic Peptide Measurement in COPD Patients with Cardiovascular Disease.
Kheir F, Salerno D.
Chest. Letter to Editor. Accepted April 2013.

Right atrium tumor thrombus.
Alraies MC, Khan UA, Alraiyes AH, Auron M.
QJM. 2012 Jul 26. PMID: 22836191

A lung cancer masquerader.
Shaheen K, Alraies MC, Alraiyes AH, Ibrahim A, Altaqi B.
QJM. 2012 Aug 8. PMID: 22875777

Bronchoesophageal Fistula Secondary to Broncholith.
Alraiyes AH, Desai R, Auron M, Castillo MD, Alraies MC.
QJM. 2012 Aug 26. PMID: 22927537

Fatal alveolar hemorrhage due to Kaposi sarcoma.
Alraies MC, Alraiyes AH, Kabach CM, Auron M.
QJM. 2012 Sep 5. PMID: 22952352

Unusual presentation of sarcoidosis--involving testis, spinal cord and the brain.
Alraies MC, Desai R, Alraiyes AH.
QJM. 2012 Sep 13. PMID: 22976618

Role of positron emission tomography in the diagnostic workup of solitary pulmonary module.
Alraies MC, Shaheen K, Alraiyes AH.
South Med J. 2012 Dec;105(12):676-7.PMID: 23211506

Menthol toxicity: an unusual cause of coma.
Baibars M, Eng S, Shaheen K, Alraiyes AH, Alraies MC.
Case Report Med. 2012;2012:187039. PMID: 23251165

A 47-year-old man with chest and neck pain.
Alraies MC, Khan UA, Shaheen K, Alraiyes AH.
Cleve Clin J Med. 2013 Jan;80(1):6-8. doi: 10.3949/ccjm.80a.12032. PMID: 23288938

Ulcerative cutaneous lesions synchronously present with the diagnosis of primary lung cancer.
Shaheen K, Alraiyes AH, Baibars M, Paintsil A, Alraies MC.
Case Rep Med. 2013;2013:136564. PMID: 23533424

Lung hernia.
Eisa N, Alraiyes AH, Shaheen K, Alraies MC.
BMJ Case Rep. 2013 Apr 29;2013. PMID: 23632188

Right coronary artery aneurysm: an unusual cause of chest pain.
Eisa N, Alamiry MR, Alraiyes AH, Alraies MC.
BMJ Case Rep. 2013 May 22;2013. PMID: 23704471

McConnell sign and S1Q3T3 pattern in pulmonary embolism: revisited.
Chamsi-Pasha MA, Aljaroudi W, Alraiyes AH, Alraies MC.
BMJ Case Rep. 2013 May 13;2013. PMID: 23674557


2011-2012 Academic Year Publications

Arsenic mediated disruption of promyelocytic leukemia protein nuclear bodies induces ganciclovir susceptibility in Epstein–Barr positive epithelial cells.
Sides MD, Block GJ, Shan B, Esteves KC, Lin Z, Flemington EK, Lasky JA.
Virology. 2011 Jul 20;416(1-2):86-97.

Epstein - Barr virus Latent Membrane Protein 1 suppresses reporter activity through modulation of Promyelocytic Leukemia Protein-Nuclear Bodies.
Sides MD, Block GJ, Chadwick RW, Shan B, Flemington EK, Lasky JA.
Virology Journal 2011, 8:461 (5 October 2011).

A Double blind, Placebo-Controlled, Randomized Trial of Combined Prednisone, Azathioprine and N-acetylcysteine in Idiopathic Pulmonary Fibrosis.
Raghu G, Anstrom KJ, King TE Jr, Lasky JA, Martinez FJ, on behalf of the IPFnet.
N Engl J Med. 2012 May 24;366(21):1968-77.

FTY720-induced conversion of conventional Foxp3- T cells to Foxp3+ regulators in NOD mice.   Wang W*, Sun Y*, Shan B*, Di J, Chen L, Ren L, Li D-J, Lin Y. 
Am J Reprod Immunol. 2011 Nov;66(5):349-362. (* denotes equal contribution)

Post-transcriptional Up-regulation of miR-21 by Type I Collagen. 
Li C, Nguyen HT, Zhuang Y, Lin Y, Flemington EK, Guo W, Guenther J, Burow ME, Morris GF, Sullivan D, Shan B.
Mol Carcinog. 2011 Jul;50(7):563-70.

Lung function, radiological changes and exposure: analysis of ATSDR data from Libby, MT, USA. Weill D, Dhillon G, Freyder , Lefante J, Glindmeyer H.
Eur Respir J. 2011 Aug;38(2):376-83.

The microRNA expression associated with morphogenesis of breast cancer cells in three-dimensional organotypic culture.
Nguyen HT, Li C, Lin Z, Flemington EK, Zhuang Y, Burow ME, Lin Y, Shan B.   
Oncol Rep. 2012 Jul;28(1): 117-126. Epub 2012 Apr 19.

Brain natriuretic peptide measurement in pulmonary medicine.
Salerno D, Marik PE.
Respir Med. 2011 Dec;105(12):1770-5. Epub 2011 Aug 6.

Randomized, placebo-controlled clinical trial of an aerosolized β₂-agonist for treatment of acute lung injury.
National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network (Simeone F listed in the appendix as one of the 188 collaborators), Matthay MA, Brower RG, Carson S, Douglas IS, Eisner M, Hite D, Holets S, Kallet RH, Liu KD, MacIntyre N, Moss M, Schoenfeld D, Steingrub J, Thompson BT.
Am J Respir Crit Care Med. 2011 Sep 1;184(5):561-8.

Enteral omega-3 fatty acid, gamma-linolenic acid, and antioxidant supplementation in acute lung injury.
Rice TW, Wheeler AP, Thompson BT, deBoisblanc BP, Steingrub J, Rock P; NIH NHLBI Acute Respiratory Distress Syndrome Network of Investigators (Simeone F  listed in the appendix as one of the 200 collaborators).
JAMA. 2011 Oct 12;306(14):1574-81. Epub 2011 Oct 5.

Initial trophic vs full enteral feeding in patients with acute lung injury: the EDEN randomized trial.
National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network (Simeone F listed in appendix as one of the 210 collaborators), Rice TW, Wheeler AP, Thompson BT, Steingrub J, Hite RD, Moss M, Morris A, Dong N, Rock P. 
JAMA. 2012 Feb 22:307(8):795-803. Epub 2012 Feb 5.

Comparison of 3 different methods used to measure the rapid shallow breathing index. Desai NR, Myers L, Simeone F.
J Crit Care. 2012 Aug;27(4):418.e1-6. Epub 2011 Sep 29.

Free-Running Disorder in a Sighted Adolescent.
Endara-Bravo AS, Thammasitboon S, Thomas D.
J Pediatr. 2012 May;160(5):877. Epub 2012 Jan 9.

Activation of autophagy in mesenchymal stem cells provides tumor stromal support. Sanchez CG, Penfornis P, Oskowitz AZ, Boonjindasup AG, Cai DZ, Dhule SS, Rowan BG, Kelekar A, Krause DS, Pochampally RR.
Carcinogenesis. 2011 Jul;32(7):964-72. Epub 2011 Feb 11.

2010-2011 Academic Year Publications

B Shan, JS Hagood, Y Zhuo, DR Levy, and JA Lasky. Thy-1 regulates TNF-alpha stimulated matrix metalloproteinase 9 expression in fibroblasts via src family kinase, PLoS One. 2010 Jul 19;5(7):e11662.

M Sides1,4, R Klingsberg2,4, B Shan3,K Gordon2, H Nguyen1, E Flemington3, JA Lasky2,5. The Epstein-Barr virus LMP 1 and TGFb1 synergistically induce EMT in human alveolar epithelial cells, Am J Respir Cell Mol Biol. 2010 Aug 6.

X Yue, B Shan, JA Lasky. TGF-b: Titan of Lung Fibrogenesis. Current Enzyme Inhibition 2010 6(2):67-77. (Review).

J. Guenther, J Cameron, H. Nguyen, Y. Wang, D. Sullivan, B. Shan, JA Lasky, E. Flemington, and G. Morris. Modulation of Lung Inflammation by the Epstein-Barr Virus Protein Zta, Am J Physiol Lung Cell Mol Physiol. 2010 Dec;299(6):L771-84. Epub 2010 Sep 3.

Raghu G, Collard HR, Egan JJ, Martinez FJ, Behr J, Brown KK, Colby TV, Cordier JF, Flaherty KR, Lasky JA, Lynch DA, Ryu JH, Swigris JJ, Wells AU, Ancochea J, Bouros D, Carvalho C, Costabel U, Ebina M, Hansell DM, Johkoh T, Kim DS, King TE Jr, Kondoh Y, Myers J, Müller NL, Nicholson AG, Richeldi L, Selman M, Dudden RF, Griss BS, Protzko SL, Schünemann HJ; on behalf of the ATS/ERS/JRS/ALAT Committee on Idiopathic Pulmonary Fibrosis. An Official ATS/ERS/JRS/ALAT Statement: Idiopathic Pulmonary Fibrosis: Evidence-based Guidelines for Diagnosis and Management. Am J Respir Crit Care Med. 2011 Mar 15;183(6):788-824.

Svitlana Danchuk, Joni H Ylostalo, Fokhrul Hossain, Randy Sorge, Austin Ramsey, Ryan W Bonvillain, Joseph A Lasky, Bruce A Bunnell, David A Welsh, Darwin J Prockop and Deborah E Sullivan. Human Multipotent Stromal Cells Attenuate LPS-Induced Acute Lung Injury in Mice via Secretion of TNF-alpha-induced Protein 6. Stem Cell Res Ther. 2011 May 13;2(3):27.

S, LaskyJA, GuoW, NguyenHT, MaiA, Danchuk FS, SullivanDE, ShanB. Pharmacological Inhibition of HDAC6 Attenuates Endothelial Barrier Dysfunction Induced by Thrombin. Biochem Biophys Res Commun. Biochem Biophys Res Commun. 2011 May 20;408(4):630-4.

Sanchez C, Penfornis P, Oskowitz AZ, Boonjindasup AG, Cai DZ, Dhule S, Rowan BG, Kelekar A, Krause DS and Pochampally R. Activation of Autophagy in Mesenchymal Stem Cells Provides Tumor Stromal Support. Carcinogenesis (2011) First published online: February 11, 2011.

Mishur RJ, Griffin ME, Battle C, Shan B, and Jayawickramarajah J. Molecular Recognition and Enhancement of Solubility and Bioactivity of CD437 by b-Cyclodextrin. Bioorg Med Chem Lett. 2011 Jan 15;21(2):857-60.

Lin Y*, Li C*, Shan B*, Wang W, Di J, Zhong Y, Li D. Reduced Expression of Stathmin-1 in NK Cells Associated with Spontaneous Abortion. Am J Pathol. 2011 Feb;178(2):506-14. (* denotes equal contribution)

Yin G, Li C, Shan B, Wang W, Chen H, Zhong Y, Di J, Lin Q, Lin Y. Insufficient Peroxiredoxin-2 Expression in Uterine NK Cells Obtained from a Murine Model of Abortion. J Cell Biochem. 2011 Mar;112(3):773-81. PMID: 21328451

Li C, Nguyen HT, Zhuang Y, Lin Y, Flemington EK, Guo W, Guenther J, Burow ME, Morris GF, Sullivan D, Shan B. Post-transcriptional Up-regulation of miR-21 by Type I Collagen. Mol Carcinog. 2011 Jul;50(7):563-70. PubMed PMID: 21647970.

Wang W*, Sun Y*, Shan B*, Di J, Chen L, Ren L, Li D-J, Lin Y. FTY720-induced conversion of conventional Foxp3- T cells to Foxp3+ regulators in NOD mice. Am J Reprod Immunol. 2011 May 27. [Epub ahead of print] PubMed PMID: 21623989. (* denotes equal contribution)

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