Molecular Biology / Lung Biology
1975, B.S., University of Georgia
1982, Ph.D., Florida State University
Mouse models of lung disease, control of cell growth, transcriptional regulation.
Recent Publications or Reports
Morris, G.F. and Brody, A.R. Molecular mechanisms of particle-induced lung disease. In: Environmental and Occupational Medicine. Fourth Edition. Rom, W.R. Ed. Little, Brown and Company, Boston, MA. (2007).
Shan B, Zhuo Y, Chin D, Morris CA, Morris GF, and Lasky JA. CDK9 is required for tumor necrosis factor-a stimulated MMP-9 expression in human lung adenocarcinoma cells. Journal of Biological Chemistry 280, 1103-1111 (2005).
Shan B. and Morris G.F. Binding sequence-dependent regulation of the human proliferating cell nuclear antigen promoter by p53. Experimental Cell Research 305, 10-22 (2005).
Morris GF, Notwick A, David O, Fermin C, Brody AR, and Friedman M. Development of lung tumors in mutant p53-expressing mice after inhalation exposure to asbestos. Chest 125, Suppl. 5, 85S-86S (2004).
Shan B. Xu J., Zhuo Y., Morris C.A. and Morris GF. Induction of p53-dependent activation of the human PCNA gene in chromatin by ionizing radiation. Journal of Biological Chemistry 278, 44009-44017 (2003).
Ghosh, S., Mendoza, T., Ortiz, L.A., Hoyle, G.W., Fermin, C.D., Brody, A.R., Friedman, M. and Morris, G.F. Enhanced bleomycin sensitivity in mice expressing dominant negative p53 from the surfactant protein C promoter. American Journal of Respiratory and Critical Care Medicine 166: 890-897 (2002).