Plasmodium vivax showing a segmenting, nearly mature schizont. Once the segmentation is complete, the schizont will rupture the RBC and release the individual merozoites. The morozoites can infect other RBCs. Vivax's cycle from infection to release takes about 48 hours. Malaria uses the Duffy antigens on the surface of the red cell to gain access. Therefore, in areas where malaria is endemic, the majority of individuals are found to be "Duffy negative." This antigen becomes important in matching blood for transfusions.
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