Click below for full list of publications

Recent Publications

González, J., Kurtz, J., Bauer, D., Hitt, R., Fitch, J., Wetzel, A., Perle, K., White, P., McLachlan, J., Gunn, J. (2019). Establishment of Chronic Typhoid Infection in a Mouse Carriage Model Involves a Type 2 Immune Shift and T and B Cell Recruitment to the Gallbladder. mBio 10(5)


Baker, S.M., Pociask, D., Clements, J.D., McLachlan, J.B., Morici, L.A., (2019). Intradermal vaccination with a Pseudomonas aeruginosa vaccine adjuvanted with a mutant bacterial ADP-ribosylating enterotoxin protects against acute pneumonia. Vaccine 37, 808–816.


Frederick, D.R., Goggins, J.A., Sabbagh, L.M., Freytag, L.C., Clements, J.D., McLachlan, J.B., (2018). Adjuvant selection regulates gut migration and phenotypic diversity of antigen-specific CD4(+) T cells following parenteral immunization. Mucosal Immunol 171, 1097.


Kurtz, J.R., Goggins, J.A., McLachlan, J.B., (2017). Salmonella infection: Interplay between the bacteria and host immune system. Immunol Lett 190, 42–50.


Spanier J.A.*, Frederick D.R.*, Taylor J.J.*, Heffernan J.R., Kotov D.I., Martinov T., Osum K.C., Ruggiero J.L., Rust B.J., Landry S.J., Jenkins M.K., McLachlan J.B.*, Fife B.T.* (2016). Efficient generation of monoclonal antibodies against peptide in the context of MHCII using magnetic enrichment. Nat Comm, 7:11804.

*authors contributed equally


Ise W., Inoue T., McLachlan J.B., Kometani K., Kubo M., Okada T., Kurosaki T. (2014). Memory B cells contribute to rapid Bcl6 expression by memory follicular helper T cells. PNAS, 111(32), 11792–11797.


Li T., Steede N.K., Nguyen H-N.P., Freytag L.C., McLachlan J.B., Mettu R.R., Robinson J.E., Landry S.J. (2014). Comprehensive analysis of contributions from protein conformational stability and major histocompatibility complex class II-peptide binding affinity to CD4+ epitope immunogenicity in HIV-1 envelope glycoprotein. J Virol, 88(17), 9605–9615.


Kurtz J.R., Petersen H.E., Frederick D.R., Morici L.A., McLachlan J.B. (2014). Vaccination with a single CD4 T cell peptide epitope from a Salmonella Type III-secreted effector protein provides protection against lethal infection. Infect Immun, 82(6), 2424-2433.


Frazier T.P., McLachlan J.B., Gimble J.M., Tucker H.A., Rowan B.G. (2014). Human Adipose-Derived Stromal/Stem Cells Induce Functional CD4(+)CD25(+)FoxP3(+)CD127(-) Regulatory T Cells Under Low Oxygen Culture Conditions. Stem Cells Dev, 23(9), 968-977.


Dutta, N. K. *, McLachlan, J. *, Mehra, S., & Kaushal, D. (2014). Humoral and lung immune responses to Mycobacterium tuberculosis infection in a primate model of protection. Trials in Vaccinology, 3, 47–51.

*authors contributed equally


Nelson R.W.*, McLachlan J.B. *, Kurtz J.R, Jenkins M.K. (2013). CD4+ T cell persistence and function after infection are maintained by low-level peptide:MHC class II presentation. J Immunol, 190(6), 2828–2834.

*authors contributed equally


Lee, S-J*, McLachlan, J.B.*, Kurtz, J.R., Fan, D., Winter, S. E., Bäumler, A.J., Jenkins, M.K., and McSorley, S.J. (2012). Temporal expression of bacterial proteins instructs host CD4 T cell expansion and Th17 development. PLoS Pathog, 8(1):e1002499.

*authors contributed equally


Nieves, W., Asakrah, S., Qazi, O., Brown, K.A., Kurtz, J., Aucoin, D.P., McLachlan, J.B., Roy, C.J., and Morici, L.A. (2011). A naturally derived outer-membrane vesicle vaccine protects against lethal pulmonary Burkholderia pseudomallei infection. Vaccine 29, 8381–8389.


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